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Generic Name : Altiplase (Tissue Plasminogen Activator)
Indication : Lysis of suspected occlusive coronary artery thrombi associated with evolving transmural MI in adults.
Contra Indication : Hypertension with possible cerebrovascular haemorrhage. Ulcerative colitis, subacute bacterial endocarditis. GI bleeding. Recent haemorrhage. Acute pancreatitis or hepatic disease, recent trauma.
Caution : Diabetes mellitus, proliferative diabetic retinopathy. Hepatic and renal impairment, recent surgery or invasive procedures.
Side Effect : Nausea, vomiting, headache, rash pruritus. Intra cerebral haemorrhage, GI and genito urinary bleeding.
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