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Generic Name : Alprostadil (Progstaglandin-E1)
Indication : Maintenance of patency of ductus arteriosus in neonates with congenital heart disease.
Contra Indication : Hypersensitivity, hyaline membrane disease.
Contraindicated during pregnancy.
Caution : Neonates receiving PGE, for more than 120 hr should be closely monitored for antral hyperplasia and gastric outlet, obstruction; history of haemorrhage; monitor BP, blood oxygenation and blood pH continually caution in COPD.
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