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Generic Name : Amphotericin B
Indication : Topically for oral, vaginal and cutaneous candidiasis and otomycosis. Most effective for various types of systemic mycoses.
Contra Indication : Renal impairment, epilepsy.
Caution : Test dose is must before giving intravenously. Adverse reactions can decrease with inclusion of hydrocortisone 0.6 mg/kg body weight in the infusion.
Side Effect : Chills, fever, aches, nausea, vomiting and dyspnoea. Thromboflebitis of the injected vein. Nephrotoxicity, (azotemia, reduced g.f.r. acidosis, hypokalemia and inability to concentrate urine). Anaemia due to bone marrow depression. CNS toxicity.
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